Many people know or at least have heard about such a drug as Ibuprofen, but not everyone knows how to take it and what is actually its effect. Pain syndromes of various origin are often found in the daily practice of a physician-therapist, which determines the growing need for effective analgesics. The pain is familiar to every person. The variety of causes of pain determines the high appeal of patients for this reason to the doctor. It should be noted that the prevalence of pain syndromes in recent years, despite the development of pharmacy, has not diminished, on the contrary, there is even a tendency to increase it, especially in chronic pain. The active substance of the drug is Ibuprofen (usually producers don’t change name because it is really popular and many people knows it by main component), a derivative of propionic acid. The drug inhibits the activity of prostaglandins. These are substances that take part in the inflammatory process.
Ibuprofen has such action:
It should not be taken on an empty stomach, but after a meal. This minimizes the risk of potential consequences. The drug is very well absorbed from the digestive tract and its highest concentration in the blood reaches a half to two hours later.
This drug is available in various dosage forms: in the form of tablets, suspension, rectal suppositories, gels, ointments. Such a variety of dosage forms is very convenient. For the treatment of myositis, arthritis, tendovaginitis, sprain is ointment is used. Rectal suppositories and suspension are used to reduce body temperature in young children. It is one of the few anti-inflammatory drugs that can be used in children (in the form of a suspension, rectal suppositories). Therefore, this medication is assigned to both adults and children. The spectrum of application of Ibuprofen is wide enough because any inflammatory diseases, as well as conditions are accompanied by pain.
Indications for use:
• Inflammatory diseases of the joints (arthritis, deforming osteoarthritis, as well as Ankylosing spondylitis);
• Fever for infectious diseases (symptomatic treatment of ARVI);
• Pain syndrome (headache, dental, muscular, menstrual pain, neuralgia, lumbalgia, ischialgia);
• Postoperative pain syndrome.
About 20% of the adult population suffers from recurring back pain lasting more than three days, of which 20% of the pain lasts more than a month and is chronic. No less acute problem is also muscular pain, which as a whole occurs in 30-85% of the population and to cope with it can Ibubrofen.
Ibuprofen dosage should be checked by physician taking into account the indications, as well as the age of the patient. As a rule, Ibuprofen is attributed to adults and children who reached the age of twelve in tablets of 200 mg three to four times a day. If necessary, the dose can be doubled: 400 mg three times a day. As soon as the expected therapeutic effect is achieved, the daily dose of the drug is reduced to 600-800 mg.
Important! The maximum daily concentration of Ibuprofen is 1200 mg. In case of exceeding this norm it is possible to develop an overdose with the drug.
It can be used by children weighing more than forty four lb from six years. Children aged six to twelve years are credited with Ibuprofen 200 mg three to four times a day. It is important that the interval between tablets is at least six hours. In the treatment of children from three months of life on prescription of the doctor the drug can be used in the form of rectal suppositories. Children aged three to nine months are prescribed one suppository (60 mg) three times a day, children from nine months to two years - one suppository (60 mg) four times a day.
In the form of an ointment or gel it is applied to the lesion site and rubbed with hands until the drug is completely absorbed three to four times a day and so for two to three weeks. It is generally well tolerated. However, in some cases, the possibility of Ibuprofen side effects is not excluded. When using any drug from the NSAID group, ulcerogenic action may be possible. This is a side effect of the drug, which is expressed in the formation of defects (ulcers) on the mucosa of the organs of the gastrointestinal tract. Given this feature, this medication should not be taken internally for more than five days. In addition, the use of drugs on an empty stomach also increases the vulnerability of the mucous membrane of the organs of the gastrointestinal tract.
Such an impressive list of undesirable effects does not at all mean that these reactions occur in all people who use Ibuprofen. They are extremely rare, but mention of them in the manufacturer's instructions is required.
Given the ulcerogenic effect of Ibuprofen, it is contraindicated in all kinds of erosive and ulcerative lesions of the digestive tract (peptic ulcer of the stomach and duodenum, NJC, Crohn's disease). It is also contraindicated in disorders of blood clotting, diseases of the optic nerve, leukopenia, thrombocytopenia, as well as hepatic, renal, heart failure. Unconditional main Ibuprofen contraindication is the presence of hypersensitivity to the components of drug. In addition, in hypersensitivity to other NSAIDs, in particular to aspirin, Ibuprofen it is also not prescribed. During pregnancy the preparation is applied only at the instruction of the doctor. Although in low concentration it still penetrates into breast milk. Because of this, lactating mothers are not recommended to use it.